Precision Surgery

Loss of nerve function can be catastrophic. As many as 80% of prostate surgeries result in incontinence or erectile dysfunction because of nerve damage, and as many as 25% of head and neck surgeries damage the facial nerves.

The mission of Alume Biosciences is to make our proprietary nerve illumination technology available for surgeons so that patients everywhere can benefit. Learn how you can help us move surgery into the light.

Dr. Quyen Nguyen, a surgeon-scientist at the University of California at San Diego, collaborated with Nobel Laureate Dr. Roger Tsien to develop our compound, which makes nerves glow during surgery. Currently in the preclinical phase, this proprietary human nerve peptide is based on their breakthrough peptide (ALM-488) and is selective for human nerves. This research earned Dr. Nguyen a Presidential Early Career Scientist Award in 2014 and has been lauded by some of the world’s top surgeons. Human clinical trials are scheduled to begin in 2020.
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Before Surgery
Patient receives ALM-488 through IV 60 minutes before surgery begins. 

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During Surgery
Illuminated nerves visible to the surgical team during patient surgery.

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After Surgery
ALM-488 is cleared through the kidneys and gone from body in hours.